Central Gain Restores Auditory Processing following Near-Complete Cochlear Denervation

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Central Gain Restores Auditory Processing following Near-Complete Cochlear Denervation

Sensory organ damage induces a host of cellular and physiological changes in the periphery and the brain. Here, we show that some aspects of auditory processing recover after profound cochlear denervation due to a progressive, compensatory plasticity at higher stages of the central auditory pathway. Lesioning >95% of cochlear nerve afferent synapses, while sparing hair cells, in adult mice virt...

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ژورنال

عنوان ژورنال: Neuron

سال: 2016

ISSN: 0896-6273

DOI: 10.1016/j.neuron.2015.12.041